. Author manuscript; available in PMC: 2006 Jun 29.

Published in final edited form as: Invest Ophthalmol Vis Sci. 2005 Nov;46(11):3922–3931. doi: 10.1167/iovs.04-1026

Table 2.

The Effect of Glucagon Receptor Antagonists (10⁻⁵ M in the Syringe, Injected Intravitreally) or Saline on the Measurements of Chick Eyes Experiencing Myopic Defocus

		Refraction (D)		Wet Weight (mg)		Axial Length (mm)
Drug (10⁻⁵M)	Treatment	Saline	Drug	Saline	Drug	Saline	Drug
des-Phe⁶	Recovery (n =6)	−1.2 ± 1.6	−6.2 ± 2.2 ^*P < 0.01	96 ± 28	67 ± 38 P = 0.16	0.80 ± 0.32	0.39 ± 0.24 ^*P = 0.03
Phe⁶	37-D lens (n =4)	2.5 ± 0.6	−2.3 ± 1.0 ^*P = 0.03	−17 ± 15	2 ± 9 P = 0.11	−0.36 ± 0.2	0.08 ± 0.15 ^*P = 0.03

Data are presented as the mean interocular difference (treated – control eye) ± SD (standard deviation of the mean).

Significant difference between saline- and drug-treated animals: Student’s t-test for des-Phe⁶-antagonist (des-Phe⁶) treatment groups (n = 6), and a Mann-Whitney non-parametric test for Phe⁶-antagonist (Phe⁶) treatment groups (n = 4).