Table 3.
The Effects of Glucagon-Related Agents (10−5 M in the Syringe, Injected Intravitreally) or Saline on Choroidal Thickness in Chick Eyes
|
Choroidal Thickness (μm) (Treated – Control eye) |
||||
|---|---|---|---|---|
| Drug (10−5M) | Treatment | Saline | Drug | PValue |
| Glucagon | FD myopia (n = 6) | 62 ± 13 | 266 ± 34 | P < 0.0001* |
| des-Phe6 | Recovery (n = 6) | 361 ± 87 | 412 ± 90 | P = 0.34 |
| Phe6 | 3 7-D lens (n = 4) | 247 ± 35 | 261 ± 24 | P = 0.67 |
Data are presented as the mean interocular difference ± SD (standard deviation of the mean).
*
indicates a significant difference between saline- and drug-treated animals using a Student’s t-test for glucagon and des-Phe6-antagonist (des-Phe6) treatment groups, n = 6, and a Mann-Whitney nonparametric test for Phe6-antagonist (Phe6) treatment groups, n = 4.