Abstract
Several different one-site, two-site, and multisite models of steady-state ion transport across a membrane are investigated. The basic features, including cooperative interactions between channels, are the same as in earlier papers in this series. In particular, the present paper represents a considerable elaboration of part III. The models might apply to artificial or possibly to biological membranes, but particular applications must await further elucidation of the molecular structure and operation of these membranes.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Adam G. Theorie der Nervenerregung als kooperativer Kationenaustausch in einem zweidimensionalen Gitter. I. Ionenstrom nach einem depolarisierenden Sprung im Membranpotential. Z Naturforsch B. 1968 Feb;23(2):181–197. [PubMed] [Google Scholar]
- Hill T. L., Chen Y. D. Cooperative effects in models of steady-state transport across membranes. II. Oscillating phase transition. Proc Natl Acad Sci U S A. 1970 May;66(1):189–196. doi: 10.1073/pnas.66.1.189. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hill T. L., Chen Y. Cooperative effects in models of steady-state transport across membranes. 3. Simulation of potassium ion transport in nerve. Proc Natl Acad Sci U S A. 1970 Jul;66(3):607–614. doi: 10.1073/pnas.66.3.607. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hill T. L., Chen Y. Cooperative effects in models of steady-state transport across membranes. I. Proc Natl Acad Sci U S A. 1970 Apr;65(4):1069–1076. doi: 10.1073/pnas.65.4.1069. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hill T. L., Kedem O. Studies in irreversible thermodynamics. 3. Models for steady state and active transport across membranes. J Theor Biol. 1966 Apr;10(3):399–441. doi: 10.1016/0022-5193(66)90136-6. [DOI] [PubMed] [Google Scholar]
- Hill T. L. Studies in irreversible thermodynamics, vii. Proc Natl Acad Sci U S A. 1966 Sep;56(3):840–844. doi: 10.1073/pnas.56.3.840. [DOI] [PMC free article] [PubMed] [Google Scholar]