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. 2000 Apr;11(4):1241–1255. doi: 10.1091/mbc.11.4.1241

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Copyright © 2000, The American Society for Cell Biology

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Markers of the TGN compartment, TGN38 and M6PR, are redistributed in cells overexpressing GGA1 or HA-GGA3. GGA1 (A and B), HA-GGA1 (C and D), or HA-GGA3 (E–H) were transiently transfected into NRK cells, as described in MATERIALS AND METHODS. Doubly labeled images are shown of cells stained for GGA1 (A) and TGN38 (B); HA-GGA1 (C) and M6PR (D); HA-GGA3 (E) and TGN38 (F); and HA-GGA3 (G) and M6PR. Note the loss of signal from TGN38 and M6PR in cells overexpressing GGAs compared with untransfected cells in the surrounding area.