Fig. 1.
Diagram of pmel-1 CD8+ transgenic T cell interaction with B16 melanoma. T cells from transgenic mice express a TCR recognizing a H-2Db-restricted CD8+ epitope from the gp100/pmel-17 protein mouse gp10025–33 (EGSRNQDWL) or human gp10025–33 (KVPRNQDWL). APC, Antigen-presenting cell.