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Examples of hemoglobin M variants
| Hemoglobin | Substitution | Clinical presentation | Reference |
| HbM Boston | α58 (His→Tyr) | Cyanosis at birth | Gerald and Efron, 1961 (50) |
| HbM Saskatoon | β63 (His→Tyr) | Cyanosis | Stavem et al, 1972 (51) |
| HbM Iwate | α87 (His→Tyr) | Cyanosis at birth | Hayashi et al, 1966 (52) |
| HbM Hyde Park | β92 (His→Tyr) | Cyanosis | Hutt et al, 1998 (53) |
| HbFM Fort Ripley | α92 (His→Tyr) | Cyanosis at birth | Hain et al, 1994 (54) |
