Table 4.
Adjusted Odds Ratios for Achievement of Low-Density Lipoprotein Cholesterol Treatment Goals in African Americans Relative to Non-Hispanic White Patients
| Model Adjusted for Risk Category Plus Each of the Following Variables | Odds Ratio (95% Confidence Interval) for LDL-C Goal Achievement in African American vs. Non-Hispanic White (Referent) Patients | P-Value for Ethnicity |
|---|---|---|
| No additional factors | 0.53 (0.42, 0.66) | <.001 |
| Age (male ≥45 y, female ≥55 y) | 0.56 (0.45, 0.70) | <.001 |
| Gender | 0.55 (0.44, 0.68) | <.001 |
| Smoking status (current vs nonsmoker) | 0.52 (0.42, 0.64) | <.001 |
| Family history of premature CHD | 0.53 (0.42, 0.65) | <.001 |
| Hypertension | 0.51 (0.41, 0.64) | <.001 |
| HDL-C<1.04 mmol/L | 0.53 (0.43. 0.66) | <.001 |
| HDL-C≥1.55 mmol/L | 0.53 (0.42, 0.65) | <.001 |
| Triglycerides≥2.26 mmol/L | 0.50 (0.40, 0.62) | <.001 |
| Obesity (body mass index≥30 kg/m2) | 0.53 (0.43, 0.66) | <.001 |
| Diabetes mellitus | 0.54 (0.42, 0.71) | <.001 |
| Drug therapy vs. no drug therapy | 0.54 (0.43, 0.68) | <.001 |
| Statin monotherapy vs. other monotherapy | 0.50 (0.39, 0.65) | <.001 |
| Statin monotherapy vs. no drug | 0.50 (0.39, 0.63) | <.001 |
| Statin monotherapy vs. combination therapy | 0.49 (0.38, 0.62) | <.001 |
| High efficacy statin vs. lower efficacy statin* | 0.49 (0.38, 0.63) | <.001 |
| Receipt of diet recommendations | 0.53 (0.42, 0.66) | <.001 |
| Primary care vs. subspecialties | 0.57 (0.45, 0.70) | <.001 |
| Multivariate model† | 0.48 (0.39, 0.60) | <.001 |
High efficacy statins included atorvastatin and simvastatin (rosuvastatin was not yet cleared for marketing at the time this survey was completed). Lower efficacy statins included lovastatin, pravastatin, and fluvastatin.
The odds ratio from the multivariate model is adjusted for age category, gender, smoking status, family history, hypertension, high-density lipoprotein cholesterol category, hypertriglyceridemia, obesity, use of lipid drug therapy, receipt of diet recommendations and physician specialty. The -2 log likelihood of the fully adjusted model was 5,215.4 without ethnicity and 5,174.1 with ethnicity included.
CHD RE, coronary heart disease risk equivalents; HDL-C, high-density lipoprotein cholesterol.