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Dosage interactions of YCG1, BRN1, and SMC2
| Gene overexpressed | Mutation
|
|||
|---|---|---|---|---|
| brn1-20 | brn1-34 | brn1-60 | smc2-8 | |
| BRN1 | + | + | + | − |
| YCG1 | ± | − | + | −* |
| SMC2 | − | − | − | + |
The indicated genes were expressed from 2-μm plasmids under the control of their respective endogenous promoters. Cells were grown on SD plates for 3 d at 37°C (brn1) or 34°C (smc2).
Prolonged incubation of smc2-8 cells overexpressing YCG1 resulted in marginal growth at 34°C.
