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. 2000 Apr;11(4):1385–1400. doi: 10.1091/mbc.11.4.1385

Figure 1.

Figure 1

TgM-D is a member of the class XIV myosins. (A) Sequence alignment of the class XIV myosins. Identical amino acids are indicated by a star; homologies are indicated by a dot. The TgM-A glutamine 419 corresponds to the TEDS site, and the serine 693 is found instead of the conserved glycine proposed to act as a pivot point of the lever arm. (B) Phylogenetic tree with 51 myosins representative of each known class. TgM-D and the completed PfM-A belong to the class XIV. (C) Schematic presentation of the constructs used in this study. The numbers on top of the bars indicate the corresponding residues from each myosin (see A). Most accession numbers can be found at http://www.mrc-lmb.cam.ac.uk/myosin/trees/accession.html, and some can be found in an article by Schwarz et al. (1999). Accession numbers for the apicomplexan myosins: TgM-A, AF006626; TgM-B, AF006627; TgM-C, AF006628; a genomic fragment with the correct 5′end of TgM-B and -C cDNAs, AF202585; TgM-D, AF105118; TgM-E, AF221131; PfM-A, AF105117; PfM-B, AF222716; and PfM-C, AF222717.