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Analysis of ADAM 23 interaction with cell lines expressing specific integrins. (A) Microtiter plates were coated with ADAM 23-GST (10 μg/ml) and seeded with parental CHO cells or with CHO cells transfected with the indicated integrins. (B) Effect of a function-blocking anti-αvβ3 antibody (LM 609) on β3-CHO and NB100 neuroblastoma cell adhesion mediated by ADAM 23. Control, control sample (without addition of antibody); LIA 1/2, samples analyzed with this blocking anti-β1 antibody.
