Fig. 6.
Nitric oxide stimulation of JNK and p38 MAP kinases. Trigeminal cultures were stained with antibodies directed against the active (phosphorylated) forms of ERK (A-D), JNK (E-H) or p38 (I-L). Unstimulated trigeminal cultures (A and B, E and F, I and J) or cultures treated with 1 mm SNAP (C and D, G and H, K and L) were stained with antibodies directed against the active (phosphorylated) forms of ERK (A-D), JNK (E-H) or p38 (I-L). Phase contrast microscopy (left panels) and fluorescence microscopy (right panels) photographs of the same culture are shown. Arrows indicate neuronal cell bodies. Scale bars, 50 μm.