TABLE 3.
Relative number of APC in spleens from mice during the acute phase of infection with T. cruzia
| Infection | Mean % of cells positive (± SD) for surface marker:
|
||
|---|---|---|---|
| CD 11c+ | Mac-3+ | CD19+ | |
| Control | 3.4 ± 0.4 | 4.0 ± 0.5 | 46.3 ± 4.3 |
| RA | 6.4 ± 1.0 | 14.2 ± 3.3∗∗ | 28.3 ± 3.3∗ |
| K98 | 4.1 ± 1.2 | 6.5 ± 0.7 | 43.2 ± 6.7 |
a
Mice were infected with the RA or K98 T. cruzi strain by footpad inoculation. Splenic single-cell suspensions were stained for PE-conjugated monoclonal antibody against the cell surface markers. Results are expressed as mean percent positive cells. ∗, P < 0.05; ∗∗, P < 0.01 compared with the control.