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. 2003 Mar;71(3):1147–1154. doi: 10.1128/IAI.71.3.1147-1154.2003

FIG. 2.

FIG. 2.

Time course of BoNT/A transport in A→B and B→A directions across Calu-3 cells (A) and rat alveolar epithelial cells (B). Monolayers were exposed for various times at 37°C to 125I-BoNT/A (10−8 M), which was added to the donor medium. At the indicated times, receptor media were removed and measured for radioactivity as described in Materials and Methods. Each data point represents an average (plus standard deviation) of three separate experiments with three replicates each.