Skip to main content
. 2003 Mar;71(3):1225–1233. doi: 10.1128/IAI.71.3.1225-1233.2003

FIG. 1.

FIG. 1.

Contrasting features of C. burnetii phase II infection of mouse PMΦ and BMMΦ. Parallel cultures of macrophages were infected for 24 h with C. burnetii phase II; at different times, the cultures were fixed and processed as described in Materials and Methods. (A) Percentage of cells with LRVs as a function of the duration of infection. Symbols: •, PMΦ; ○, BMMΦ. (B) Relative bacterial load in LRVs on days 4 and 6 after infection. Bars: □, PMΦ; ▪, BMMΦ. Data represent the mean ± the standard deviation of one representative experiment out of five with similar results. Asterisks indicate statistically significant differences between PMΦ and BMMΦ (✽, P < 0.05; ✽✽, P < 0.01). (C and D) Superimposed confocal images of DAPI fluorescence (black) and Nomarski differential interference contrast (gray) of a representative PMΦ (C) and BMMΦ (D). The arrow points to large vacuole. N, cell nuclei. Bar, 10 μm.