FIG. 6.

Effect of IFN-γ, AG, or both, on C. burnetii viability in BMMΦ. IFN-γ, AG, or both were added to the cultures, together with the bacteria, for 24 h. At that time the cells were washed and kept in fresh drug-containing medium. At 6 days after infection, supernatants were collected for nitrite determination and the bacterial viability was determined as described in Materials and Methods. (A) Macrophages obtained from WT mice; (B) macrophages obtained from iNOS KO mice. The results are given as the relative infection index (FFU) as the means ± the standard errors of one representative experiment from two with similar results.