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. 2003 Mar;71(3):1274–1280. doi: 10.1128/IAI.71.3.1274-1280.2003

FIG. 5.

FIG. 5.

Bioassays of the pro- and mature IL-18 cleaved products. NKO cells were stimulated with proIL-18 (A) and mature IL-18 (B) that was cleaved, uncleaved, or cleaved in the presence of inhibitor (E-64) samples at concentrations shown under the horizontal axis in the presence of IL-12 (0.5 to 1.0 ng/ml). After 24 h, IFN-γ was measured at the concentration shown to the left of the vertical axes. The data represent means ± standard errors of the means (n = 3).