Table 3.
The ORs for CRC of APC genotypes at g.1458T>C, g.4479G>A, g.5268T>G and g.5465A>T.
| Variant | Genotype | Numbers in healthy/patient group | OR (95% CI$) | p* |
| g.1458T>C | TT | 2/5 | 1.65 (0.31 – 8.93) | NS# |
| TC | 31/13 | 0.28 (0.13 – 0.59) | 0.001 | |
| CC | 41/62 | 1 | ||
| g.4479G>A | GG | 2/0 | 0 | NS |
| GA | 23/11 | 0.34 (0.15 – 0.76) | 0.009 | |
| AA | 49/69 | 1 | ||
| g.5268T>G | TT | 7/0 | 0 | NS |
| TG | 23/17 | 0.52 (0.25 – 1.08) | 0.078** | |
| GG | 44/63 | 1 | ||
| g.5465A>T | AA | 64/78 | 1 | |
| AT | 10/2 | 0.16 (0.03 – 0.78) | 0.023 | |
| TT | 0/0 | |||
$CI: Confidence interval.
*: The p value was obtained by logistic regression.
**: Close to significant.
#NS: Not significant.