Table 5.
# | SNP ID | Variation Allele 1/2 | Observed genotype frequencies | Observed allele frequencies | Hardy-Wenberg | ||||
Homo Allele 1 | Hetero | Homo Allele 2 | Allele 1 | Allele 2 | Expect heterozygous | P value | |||
1 | rs10504255 | A/G | 0.71 | 0.25 | 0.03 | 0.84 | 0.16 | 0.27 | 0.79 |
2 | rs8192879 | C/T | 0.41 | 0.42 | 0.18 | 0.61 | 0.39 | 0.47 | 0.34 |
3 | rs11786580 | C/T | 0.75 | 0.25 | 0 | 0.87 | 0.13 | 0.22 | 0.45 |
4 | rs8192874 | T/C | 1.00 | 0 | 0 | 1.00 | 0 | ||
5 | rs2162459 | A/G | 0.59 | 0.31 | 0.10 | 0.75 | 0.25 | 0.38 | 0.13 |
6 | rs3808607 | T/G | 0.62 | 0.30 | 0.09 | 0.76 | 0.24 | 0.37 | 0.09 |
7 | rs7833904 | T/A | 0.64 | 0.30 | 0.07 | 0.79 | 0.21 | 0.33 | 0.37 |
8 | rs1125226 | A/C | 0.62 | 0.30 | 0.08 | 0.78 | 0.22 | 0.34 | 0.18 |
9 | rs1023652 | C/G | 0.67 | 0.26 | 0.07 | 0.81 | 0.19 | 0.32 | 0.14 |
10 | 1302 delTT | TT/– | 1.00 | 0 | 0 | 1.00 | 0 | ||
B. in the African-American population | |||||||||
1 | rs10504255 | A/G | 0.81 | 0.18 | 0.01 | 0.84 | 0.10 | 0.18 | 1.00 |
2 | rs8192879 | C/T | 0.56 | 0.36 | 0.08 | 0.61 | 0.26 | 0.38 | 0.82 |
3 | rs11786580 | C/T | 0.60 | 0.36 | 0.04 | 0.87 | 0.22 | 0.34 | 0.90 |
4 | rs8192874 | T/C | 1.00 | 0 | 0 | 1.00 | 0 | ||
5 | rs2162459 | A/G | 0.25 | 0.34 | 0.41 | 0.75 | 0.58 | 0.49 | 0.01 |
6 | rs3808607 | T/G | 0.23 | 0.36 | 0.40 | 0.76 | 0.58 | 0.49 | 0.03 |
7 | rs7833904 | T/A | 0.20 | 0.50 | 0.30 | 0.79 | 0.55 | 0.50 | 1.00 |
8 | rs1125226 | A/C | 0.20 | 0.49 | 0.31 | 0.78 | 0.56 | 0.49 | 1.00 |
9 | rs1023652 | C/G | 0.33 | 0.38 | 0.29 | 0.81 | 0.49 | 0.50 | 0.04 |
10 | 1302 delTT | TT/-- | 1.00 | 0 | 0 | 1.00 | 0 |
* Shadows indicate SNP nucleotides in P1 probe and target sequences.