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. 2006 May 18;7:29. doi: 10.1186/1471-2156-7-29

Table 5.

Allele frequencies of the selected CYP7A1 htSNPs and mutation markers A. in the Mexican-American population.

# SNP ID Variation Allele 1/2 Observed genotype frequencies Observed allele frequencies Hardy-Wenberg

Homo Allele 1 Hetero Homo Allele 2 Allele 1 Allele 2 Expect heterozygous P value
1 rs10504255 A/G 0.71 0.25 0.03 0.84 0.16 0.27 0.79
2 rs8192879 C/T 0.41 0.42 0.18 0.61 0.39 0.47 0.34
3 rs11786580 C/T 0.75 0.25 0 0.87 0.13 0.22 0.45
4 rs8192874 T/C 1.00 0 0 1.00 0
5 rs2162459 A/G 0.59 0.31 0.10 0.75 0.25 0.38 0.13
6 rs3808607 T/G 0.62 0.30 0.09 0.76 0.24 0.37 0.09
7 rs7833904 T/A 0.64 0.30 0.07 0.79 0.21 0.33 0.37
8 rs1125226 A/C 0.62 0.30 0.08 0.78 0.22 0.34 0.18
9 rs1023652 C/G 0.67 0.26 0.07 0.81 0.19 0.32 0.14
10 1302 delTT TT/– 1.00 0 0 1.00 0

B. in the African-American population

1 rs10504255 A/G 0.81 0.18 0.01 0.84 0.10 0.18 1.00
2 rs8192879 C/T 0.56 0.36 0.08 0.61 0.26 0.38 0.82
3 rs11786580 C/T 0.60 0.36 0.04 0.87 0.22 0.34 0.90
4 rs8192874 T/C 1.00 0 0 1.00 0
5 rs2162459 A/G 0.25 0.34 0.41 0.75 0.58 0.49 0.01
6 rs3808607 T/G 0.23 0.36 0.40 0.76 0.58 0.49 0.03
7 rs7833904 T/A 0.20 0.50 0.30 0.79 0.55 0.50 1.00
8 rs1125226 A/C 0.20 0.49 0.31 0.78 0.56 0.49 1.00
9 rs1023652 C/G 0.33 0.38 0.29 0.81 0.49 0.50 0.04
10 1302 delTT TT/-- 1.00 0 0 1.00 0

* Shadows indicate SNP nucleotides in P1 probe and target sequences.