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. 2006 Jul;80(13):6697–6701. doi: 10.1128/JVI.02388-05

FIG. 3.

FIG. 3.

B19 HLA-A24 FYTPLADQF-specific T-cell responses show striking BV5.1 TCR usage and efficient cytolysis. (A) BV5.1 usage of HLA-A24 FYTPLADQF tetramer-positive T cells from six acute and one remote responder. (B) Longitudinal BV5.1 monoclonal antibody staining of PBMC from acutely infected patient O1. (C) Chromium release cytolysis (using HLA-A24-positive or -negative B-cell targets) of HLA-A24 FYTPLADQF-specific CD8+ T-cell clone O22 clone 1. The peptide concentration for the left panel was 10−6 M, and the E:T ratio in the right panel was 1:1.