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Growth of recombinant Ebola viruses and production of RANTES during infection of Vero E6 cells with recombinant Ebola viruses. The growth of the recEBO-VP35/wt, recEBO-VP35/R305A, and recEBO-VP35/R312A viruses was measured in Vero E6 cells at an MOI of 0.02 (A) or 2 (B). Virus titer was determined by standard immunoplaque assay. RANTES was measured in the supernatants from the growth curves by an ELISA. The cells had been infected at an MOI of 0.02 (C) or 2 (D).
