TABLE 1.
Summary of marburgvirus diagnostic test results for samples sent to CDC from Angola in March 2005
| Specimen no. (last four digits) | Patient age | Specimen type | Diagnostic test results
|
|||||
|---|---|---|---|---|---|---|---|---|
| Aga | IgM | IgG | Q-RT-PCRb | Virus isolationc | IHC staining | |||
| 1377 | 12 yr | Serum | − | − | − | ++ | + | NDd |
| 1378 | 16 mo | Serum | − | − | − | ++ | + | ND |
| 1379 | 8 mo | Serum | +++ | − | − | ++++ | + | ND |
| 1380 | 3 yr | Serum | ++ | − | − | ++++ | + | ND |
| 1381 | 9 mo | Serum | − | − | − | +++ | + | ND |
| 1382 | NAe | Serum | − | − | − | − | − | ND |
| 1383 | NA | Serum | − | − | − | − | − | ND |
| 1384 | NA | Serum | − | − | − | − | − | ND |
| 1385 | 24 yr | Serum | − | − | − | + | + | ND |
| 1386 | 5 yr | Serum | + | − | − | ++ | + | ND |
| 1387 | 5 yr | Serum | − | − | − | +++ | + | ND |
| 1388 | NA | Serum | + | − | − | ++ | − | ND |
| 1411f | 51 yr | Blood | − | − | − | +++ | + | ND |
| 1412f | 51 yr | Serum | − | − | − | ++ | + | ND |
| 1413 | NA | Skin | ND | ND | ND | ND | ND | + |
a
Antigen capture assay. +++, sum optical density (23) of greater than 2.0; ++, sum optical density of 1.0 to 2.0; +, sum optical density of 0.45 (threshold) to 1.0.
b
++++, CT values of less than 20; +++, CT values of 20 to 25; ++, CT values of 25 to 30; +, CT values of 30 to 35.
c
Virus isolations were considered positive after cultures of Vero E6 cells showed cytopathic effect and subsequent scrapes were positive by immunofluorescence assay.
d
ND, not determined.
e
NA, not available.
f
Case in the capital, Luanda.