Skip to main content

TABLE 1.

Genotyping analyses reveal that dph3−/− mice are embryonic lethal

Developmental stage No. of progeny
Genotyped as:
Reabsorbedb Total
+/+ +/− −/−a
Adult 54 89 0 143
E12.5 11 27 0 18 56
E11.5 7 7 0 7 21
E10.5 11 20 7* 38
E9.5 20 38 17* 75
E8.5 8 24 8* 40
a

* indicates abnormal, small embryos.

b

Reabsorbed embryos cannot be genotyped because only abnormal placentas fusing with dead embryos were found in these sites. These sites are likely to be the missing homozygous embryos.