Figure 4.

Inhibition of inward Na⁺ currents through NSCCs by external acidification. pH values are indicated (d_p = 23.5 mm). Inset shows dose-response relation (d_p = 22.5 ± 0.8 μm; n = 4; ±se). G/G_max is the ratio between conductance recorded at the tested pH (G) and maximal conductance registered at pH 9.5 (G_max). Conductance values are conductances for inward current immediately negative of the reversal potential. Solutions contained 100 mm NaCl. Data were fitted by sigmoidal function (Hill, four parameters) by Sigma Plot software. P_K was determined graphically.