Figure 1.

Current/voltage relationship of AtCNGC2 currents recorded from oocytes (two-electrode configuration) with a range of monovalent cations in the perfusion bath. All currents (except for the control) are presented as leak subtracted recordings. Command voltages were applied in 20-mV steps between +60 and −160 mV. For each monovalent cation shown, currents were recorded with a bath solution lacking dibutyryl-cAMP. cAMP-activated currents were recorded after 40 min perfusion with dibutyryl-cAMP. In each case, the leak current was subtracted from the cAMP-activated current, yielding the current values shown at each command voltage tested. The control treatment was recorded with KCl and dibutyryl-cAMP in the bath. Current values are presented as means (n = 6 [control], 11 [K⁺], 8 [Na⁺], 7 [Cs⁺], 6 [Rb⁺], and 4 [Li⁺]) ± se.