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. 2006 Jul;80(14):7028–7036. doi: 10.1128/JVI.00478-06

FIG. 6.

FIG. 6.

rwtVSV and VSVΔM51 pathology in knockout (K/O) mice. (A) Weight loss in C57BL/6 (+/+, filled circles) or TNF-α K/O (−/−, open circles) mice following i.n. infection with rwtVSV. Error bars represent standard errors of the means (n = 5). (B) Weight loss in C57BL/6 (+/+, filled triangles) or TNF-α K/O (−/−, open triangles) mice following i.n. infection with VSVΔM51. Error bars represent standard errors of the means (n = 5). (C) Weight loss in mock-infected control C57BL/6 (+/+, filled squares) or TNF-α K/O (−/−, open squares) mice following i.n. administration of DMEM. Error bars represent standard errors of the means (n = 5). (D) Viral titers in plasma 24 h post-rwtVSV infection in C57BL/6 and TNF-α K/O mice. Error bars represent standard errors of the means (n = 3). (E) IFN-α levels, obtained by ELISA, in mouse plasma 24 h post-rwtVSV infection in C57BL/6 and TNF-α K/O mice. Plasma was pooled from three mice. (F) nAb titers to VSV G in sera of C57BL/6 and TNF-α K/O mice 28 days postinfection with rwtVSV. Error bars represent standard errors of the means (n = 3).