Figure 1.

Phenotypes of TUB1 and TUB2 Ala-scan mutants. The positions of the mutations and their resulting phenotypes are shown for both TUB1 (top) and TUB2 (bottom). The allele number of each mutation is shown, and the altered residues are in bold. SS, benomyl-supersensitive; R, benomyl-resistant; WT, wild-type; CS, cold-sensitive; TS, heat-sensitive; SLOW, slow growth at all temperatures. The TUB2 Ala-scan data is reproduced from Reijo et al. (1994), and phenotype definitions are adapted to be identical to those used in describing the TUB1 mutants.