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. 2006 Jun;26(12):4539–4552. doi: 10.1128/MCB.02120-05

FIG. 7.

FIG. 7.

Analysis of the E11 gene sequence (accession no. AY115493) used for these studies. AY115493 is the sequence we submitted and published in GenBank from the 129 mouse strain. NT_094216 (MM4_93853_34, genome) is a Mus musculus strain 129 chromosome 4 genomic contig. NT_039267 (MM4_39307_34) is a M. musculus strain C57BL/6J chromosome 4 genomic contig. AC098724 is M. musculus strain C57BL/6J bacterial artificial chromosome clone RP23-3D14 from chromosome 4. AL611982 is a mouse DNA sequence from clone RP23-348F1 on chromosome 4, also from strain C57BL/6J. Therefore, the C57BL/6J strain contains an SmaI cleavage site at this position in the promoter whereas the 129 mouse strain does not. Sequence analysis with the Transcription Element Search System revealed Ets-2 and Pit-1a binding sites in part of the deleted sequence. Several Sp1 sites and an Ap-1 site are also present in the deleted sequence, nucleotides 9680 to 10137. The nucleotide position numbering is that in the original GenBank sequence file. (R) indicates that the transcription factor recognizes the reverse complement sequence.