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. 2006 Jun;26(12):4399–4409. doi: 10.1128/MCB.01147-05

FIG. 6.

FIG. 6.

FA formation and FAK pY397 levels in SFK-null fibroblasts and cells reexpressing Src SH2 domain mutants after removal of the microtubule-depolymerizing agent nocodazole. (A) Vinculin staining of SYF cells and cells expressing SrcR175L and SrcR175L-FAT at various times after nocodazole washout. (B) Phosphorylation of FAK Y397 in SrcR175L and SrcR175L-FAT cells at 0, 15, 30, 60, and 120 min after nocodazole washout. The chart represents the average relative pY397 levels (± standard errors of the means) at the same time points from two independent experiments. FA regeneration and recovery of FAK phosphorylation after nocodazole washout are restored in SrcR175L cells by targeting the kinase to FAs.