Functional grouping of deletion mutant sensitivity data. (A) Localization was assigned based on the “Component” term of the Saccharomyces Genome Database GO term mapper. Cyt, cytoplasm; Nuc, nucleus; Mit, mitochondrion; Golgi, Golgi apparatus; ER, endoplasmic reticulum; Vac, vacuole; Plasma/bud, plasma membrane and bud; O/U, other/unknown. (B) Gene products were grouped into functional categories according to the MIPS functional database and the Saccharomyces Genome Database, combined with visual inspection. More-detailed functional data are available in Table 1. PS, protein synthesis; Cell, cell cycle and differentiation; Signal, cellular communication/signal transduction; Metab, metabolism; Transport, cellular transport; Transcript, transcription; Prot fate, protein fate; O/U, other/unknown.