TABLE 2.
Classification | Gene(s) | Pathway |
---|---|---|
Biosynthetic pathways | argC, D, E, G | Arginine biosynthesis |
aroB | Chorismate biosynthesis | |
bioA, B | Biotin biosynthesis | |
carB | Pyrimidine and arginine biosynthesis | |
cvpA | Colicin V biosynthesis | |
cysD, G, J, Q | Sulfur metabolism | |
entB, F | Enterobactin biosynthesis | |
hflD | Membrane protein in operon with purB | |
hisB | Histidine biosynthesis | |
ilvA, C, D | Valine, isoleucine biosynthesis | |
leuA, B, C | Leucine biosynthesis | |
menD | Menaquinone biosynthesis | |
metA, B, C, E | Methionine biosynthesis | |
panB, C | Pantothenate biosynthesis | |
pdxB | Pyridoxal 5′-phosphate biosynthesis | |
proA | Proline biosynthesis | |
purC, H | Purine nucleotide biosynthesis | |
pyrD, F | Pyrimidine ribonucleotide biosynthesis | |
rfaG | Lipopolysaccharide core biosynthesis | |
serA, C | Serine biosynthesis | |
thiC | Thiamine biosynthesis | |
thrA | Homoserine biosynthesis | |
trpA, B, C, E | Tryptophan biosynthesis | |
tyrA | Phenylalanine/tyrosine biosynthesis | |
Catabolism | fruK | 1-Phosphofructokinase |
gltA | Citrate synthase | |
mtlA | Subunit of EIImtlA | |
pgi | Phosphoglucose isomerase | |
ppc | Phosphoenolpyruvate carboxylase | |
Regulation | argP | Transcriptional regulator |
cspA | Transcriptional activator | |
cysB | Transcriptional regulator | |
ilvY | Transcriptional regulator | |
Transporters | nirC | Nitrite transporter |
cysP | Thiosulfate ABC transporter | |
glcA | Glycolate transporter | |
xylE | Xylose major facilitator superfamily transporter | |
Essential genes | lhr | Member of ATP-dependent helicase superfamily II |
mraZ | Member of dcw cluster (cell division) | |
prmA | Methylation of 50S ribosomal subunit protein L11 | |
rplM | L13 protein of 50S ribosomal subunit | |
sfmH | Involved in fimbrial assembly | |
truA | Pseudouridylate synthase I | |
Unknown function | b3557 | IS5-related protein |
ydeO | Putative AraC-type regulatory protein | |
yfgL | Putative dehydrogenase | |
yhdP | Putative transport protein | |
yidL | Putative AraC-type regulatory protein | |
yjhF | Member of Gnt transporter family | |
ykgC | Putative oxidoreductase | |
yrbK | Conserved hypothetical protein |
Genes are classified depending on their function; regulatable candidates are shown in boldface type.