FIG. 6.

Flux estimates for ¹³C-based MFA of P. chrysogenum. Values in gray type represent the drain on the primary metabolites for monomer synthesis (e.g., amino acids, polysaccharides, fatty acids, nucleotides etc.). Fluxes are normalized for the glucose uptake rate. Values not in parentheses indicate the net fluxes, while values in parentheses indicate the exchange fluxes. The arrows with the solid arrowheads indicate the direction of the net flux. e4p, erythrose-4-phosphate; E-C₂, glycolaldehyde moiety covalently bound to the thiamine pyrophosphate/transketolase complex; E-C₃, dihydroxyacetone moiety covalently bound to the enzyme transaldolase; p5p, combined pool of xylulose-5-phosphate, ribose-5-phosphate, and ribulose-5-phosphate; g3p, glyceraldehyde-3-phosphate; oaa, oxaloacetate; s7p, sedoheptulose-7-phosphate.