TABLE 1.
Characteristics of M. tuberculosis complex strains and mgtC polymorphism based on DNA sequences
| Strain | Sourcea | Species | Groupb | Genotype | Country of isolation | mgtC polymorphismc |
|---|---|---|---|---|---|---|
| CIP 0357 | a | M. tuberculosis | 1 | Beijing | Cambodia | wt |
| CIP 1121 | a | M. tuberculosis | 1 | Beijing | France (Reunion) | wt |
| ITM 022488 | b | M. tuberculosis | 1 | Beijing | Bangladesh | wt |
| ITM 981274 | b | M. tuberculosis | 1 | Beijing | Siberia | wt |
| CIP 1008 | a | M. tuberculosis | 1 | EAI | India | wt |
| CIP 0423 | a | M. tuberculosis | 1 | EAI | France | Val GTC 87 ATC Ile |
| ITM 021038 | b | M. tuberculosis | 1 | EAI | Bangladesh | wt |
| ITM 021071 | b | M. tuberculosis | 1 | EAI | Bangladesh | wt |
| CIP 0443 | a | M. tuberculosis | 2 | Haarlem | Algeria | Arg CGC 182 CAC His |
| CIP 0276 | a | M. tuberculosis | 2 | Haarlem | France | Arg CGC 182 CAC His |
| 14 | c | M. tuberculosis | 2 | Haarlem | Burkina Faso | Arg CGC 182 CAC His |
| 45 | c | M. tuberculosis | 2 | Haarlem | Burkina Faso | Arg CGC 182 CAC His |
| 83 | c | M. tuberculosis | 2 | Haarlem | Burkina Faso | Arg CGC 182 CAC His |
| ITM 8613 | b | M. tuberculosis | 2 | Haarlem | The Netherlands | Arg CGC 182 CAC His |
| ITM 020284 | b | M. tuberculosis | 2 | Haarlem | Bangladesh | Arg CGC 182 CAC His |
| ITM 981269 | b | M. tuberculosis | 2 | Haarlem | Siberia | Arg CGC 182 CAC His |
| 2 | c | M. tuberculosis | 2 | LAM10 | Burkina Faso | wt |
| 32 | c | M. tuberculosis | 2 | LAM10 | Burkina Faso | wt |
| 3 | c | M. tuberculosis | 2 | T1 | Burkina Faso | wt |
| 19 | c | M. tuberculosis | 2 | T1 | Burkina Faso | wt |
| 17 | c | M. tuberculosis | 2 | T1 | Burkina Faso | wt |
| 42 | c | M. tuberculosis | 2 | T1 | Burkina Faso | wt |
| 27 | c | M. tuberculosis | 2 | ST200 | Burkina Faso | wt |
| 15 | c | M. tuberculosis | 2 | ST494 | Burkina Faso | wt |
| CDC 1551 | e | M. tuberculosis | 2 | United States | wt | |
| H37Rv | e | M. tuberculosis | 3 | United States | wt | |
| Erdman | f | M. tuberculosis | United States | Arg CGC 182 CAC His | ||
| ITM 010012 | b | M. africanum | Belgium | wt | ||
| ITM 993123 | b | M. africanum | Belgium | wt | ||
| 2 | d | M. bovis BCG | The Netherlands | wt | ||
| 71 | d | M. bovis BCG | Japan | wt | ||
| 76 | d | M. bovis | Argentina | wt | ||
| 25 | d | M. microti | United Kingdom | wt | ||
| 116 | d | “M. canettii” | Somalia | Val GTT 15 GTC Val |
a
Source: a, C. Gutierrez; b, F. Portaels; c, S. Godreuil; d, K. Kremer; e, published genomes; f, mgtC sequence from Erdman strain was determined in the course of a previous study (3).
b
Determined in this study by on/off switch assay (except for CDC1551 and H37Rv).
c
The wild-type (wt) sequence refers to the one found in the reference strain H37Rv.