TABLE 3.
β-Lactamase | Porin lossb | CAZ or CTXc | Clavulanic acid response | FOXd | APB response | IPMd | EDTA response |
---|---|---|---|---|---|---|---|
ESBL | − | P | Yese | S | No | S | No |
+ | P | Yes | R | No | S | No | |
AmpC | − | P | No | R | Yes | S | No |
+ | P | No | R | Nof | R/↓S | No | |
Carbapenemase class A | − | P | Yes | S | No | ↓S | No |
+ | P | Yes | R | No | ↓S | No | |
Carbapenemase class B | − | P | No | R | No | ↓S | Yes |
+ | P | No | R | No | R | Yes |
CAZ, ceftazidime; CTX, cefotaxime; FOX, cefoxitin; IPM, imipenem.
Loss of porins OmpK35 and OmpK36 in K. pneumoniae.
P, positive CLSI screening test result.
R, resistant; S, susceptible; ↓S, decreased susceptibility by CLSI disk interpretive criteria.
The enhancement of the zone of inhibition was ≥5 mm.
For AmpC, an APB response was seen with CAZ or CTX but not FOX.