TABLE 2.
Diagnostic performance of the IgG immunoassays based on recombinant antigensa
| IgG Rec-ELISA antigen | Pb | Sensitivity (%) | Specificity (%) | Agreement (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|
| GST-MIC2 | <0.0001 | 92 | 100 | 94.8 | 100 | 87.1 |
| GST-MIC3 | <0.0001 | 90 | 100 | 93.5 | 100 | 84.4 |
| GST-SAG1 | <0.0001 | 82 | 100 | 88.3 | 100 | 75 |
| GST-GRA3 | <0.0001 | 82 | 100 | 88.3 | 100 | 75 |
| GST-GRA7 | <0.0001 | 88 | 100 | 92.2 | 100 | 81.8 |
| GST-M2AP | <0.0001 | 78 | 100 | 85.7 | 100 | 71.1 |
| GST-EC2 | <0.0001 | 100 | 100 | 100 | 100 | 100 |
| GST-EC3 | <0.0001 | 100 | 100 | 100 | 100 | 100 |
a
PPV, positive predictive value; NPV, negative predictive value.
b
P values were determined by the chi-square test by comparison of the results for the Toxoplasma IgG-positive sera (group A; n = 50) and the IgG-negative sera (group C; n = 27).