TABLE 5.

Toxoplasma-specific IgM reactivities of serum samples from infants with congenital toxoplasmosis^a

Patient no.	Time after birth (wk)	Onsetb	IgG level (IU/ml)	Cutoffc		IgM Rec-ELISA cutoffd
				ELFA-Toxo-IgM	ETI-TOXOK-M	GST-EC2	GST-EC3
T1	1	B	169	6.41	2.66	2.479	0.542
T2	2	B	988	0.73	0.15	0.360	0.270
T3	2	Sub	300	0.09	0.13	0.212	0.209
T4	3	Sub	57	0.05	0.23	0.206	0.211
T5	3	Sub	124	0.13	1.62	0.641	1.103
T6	4	Sub	218	0.04	0.09	0.452	0.269
T7	4	S	157	2.61	1.62	1.522	0.225
T8	4	S	172	3.98	1.50	1.804	0.353
T9	5	S	1147	0.07	0.10	0.519	0.206
T10	5	B	47	0.11	0.12	0.272	0.276
T11	6	Sub	28	0.10	0.18	2.617	0.731
T12	6	Sub	136	0.07	0.11	0.314	0.216
T13	7	S	209	0.88	0.47	0.683	0.217
T14	8	Sub	43	0.06	0.07	0.196	0.213
T15	8	B	160	0.82	0.08	0.206	0.219
T16	8	B	64	0.02	0.40	0.231	0.228
T17	8	Sub	145	0.31	0.57	0.985	0.314
T18	9	Sub	300	6.37	1.30	0.548	0.315
T19	12	Sub	196	0.05	0.17	0.463	0.268
T20	12	Sub	75	0.05	0.07	0.237	0.222

^aSerum samples (samples T1 to T20) were analyzed by IgM Rec-ELISAs with GST-EC2 and GST-EC3 antigens or by commercial assays (ELFA-IgM and ETI-TOXO-M).

^bSeverity of clinical onset: S, severe; B, benign; Sub, subclinical.

^cThe cutoff values for the ELFA-IgM and ETI-TOXO-M assays were 0.65 and 0.41, respectively, as indicated by manufacturers. Boldface type, values greater than the cutoff value.

^dThe cutoff values for the IgM Rec-ELISA with the GST-EC2 and GST-EC3 antigens, calculated with sera from uninfected infants (n = 10), were 0.25 and 0.26, respectively. Boldface type, values greater than the cutoff value.