TABLE 1.
Baseline characteristics for pharmacokinetic populationa
| Characteristic | Value |
|---|---|
| Mean ± SD age (yr)b | 42.5 ± 7.6 |
| Mean ± SD wt (kg)b | 67.9 ± 7.6 |
| Mean ± SD ht (cm)b | 175.1 ± 7.9 |
| No. (%) of patients of male gender | 19 (100) |
| No. (%) of patients of white ethnicity | 15 (79) |
| Median (range) duration of APV-RTV treatment (mo) | 5.8 (0.5-19.2) |
| No. (%) of patients taking two RTIs | 12 (63) |
| No. (%) of patients taking three RTIs | 7 (37) |
| Median (range)c CD4 cell count (no. of cells/mm3) | 233 (12-426) |
| Median (range)c plasma HIV-1 RNA; load (log10 copies/ml) | 3.80 (<1.3-5.76) |
a
Abbreviations: SD, standard deviation; APV, amprenavir; RTV, ritonavir; RTIs, reverse transcriptase inhibitors, including efavirenz and nevirapine. A total of 19 patients were included in the pharmacokinetic population.
b
Geometric mean ± standard deviation.
c
Median interquantile range.