FIG. 3.

Schematic presentation of the biosynthesis of class IIa bacteriocins. The ribosomally produced prebacteriocin and preinducer peptide are matured and secreted through the ABC transporter. Mature inducer peptide interacts with its receptor (the histidine kinase [HK]), which is autophosphorylated at the cytosolic side. The phosphate group is subsequently transferred to the response regulator (RR), which then becomes active, enabling it to function as a transcriptional activator for bacteriocin-related genes.