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. 2006 Jun;13(6):605–610. doi: 10.1128/CVI.00123-06

FIG. 2.

FIG. 2.

Geometric mean severalfold increases (postchallenge/prechallenge) in relation to serum IgG anticapsular antibody concentrations prior to challenge with MPSV. Among subjects with ≤2 μg/ml of antibody immediately before the challenge, the statistical significance of the differences between the geometric mean (Geo. M.) severalfold increase of the MCV/naïve group versus the PCV/naïve group was a P value of <0.001, that versus the MCV/MPSV group that received MPSV <3 years prior to enrollment was a P value of <0.01, and that versus the MCV/MPSV group that received MPSV ≥3 years prior to enrollment group was a P value of <0.05. The MCV/MPSV group that received MPSV ≥3 years prior to enrollment also had higher responses to the challenge dose than the group that received MPSV <3 years before enrollment (P = 0.03). All other respective differences are not significant (P > 0.1).