TABLE 1.
Meningococcal strains used in this study
| Strain (reference[s]) | Country of origin | Yr isolated | FHBP variant group | Serologic classification | Electrophoretic type (sequence type)a |
|---|---|---|---|---|---|
| MC58 (12, 20) | United Kingdom | 1985 | 1 | B:15:P1.7,16 | ET5 complex (74) |
| MC58ΔFHBP (11) | United Kingdom | 1985 | Not applicable | B:15:P1.7,16 | ET5 complex (74) |
| 4243 (14) | United States | 1994 | 1b | C:2a:P1.5,2 | ET37 complex (11) |
| M6190 | United States | 1999 | 1b | B:2a:P1.5,2 | ET37 complex (1988) |
| NZ98/254 (10) | New Zealand | 1998 | 1b | B:4:P1.4 | Lineage 3 (42) |
| M1390 | United States | 1995 | 1b | B:15:P1.7,4 | Lineage 3 (41) |
| M4105 | United States | 1996 | 1b | B:4,7:P1.7,4 | Lineage 3 (154) |
| Z2491 (5) | The Gambia | 1983 | 1b | A:4:P1.7 | Subgroup IV-1 (4) |
| RM1090 | United States | Pre-1995 | 2b | C:2a:P1.5-1,2-2 | Unknown |
| 961-5945 | Austria | 1996 | 2 | B:2b:P1.21,16 | A4 (153) |
| 2996 (22) | United Kingdom | 1975 | 2 | B:2b:P1.19,15 | Unknown (540) |
| 8047 | United States | 1978 | 2 | B:2b:P1.5-1,2-2 | Unknown |
| M1239 | United States | 1994 | 3 | B:14:P1.23,14 | Lineage 3 (437) |
| M01-0240364 | United Kingdom | 2001 | 3 | B:2a:P1.5,2 | ET37 complex (11) |
a
Sequence type was determined previously by multilocus sequence typing (http://www.mlst.net).
b
Subvariants of the primary group as defined by the FHBP gene sequence from MC58 (variant 1) or 2996 (variant 2).