TABLE 2.
FHBP-deduced amino acid sequence identity among selected isolates from patients in Californiaa
| Strain | QPCR variant | FHBP amino acid sequence identity (%)
|
||
|---|---|---|---|---|
| MC58 (variant 1) | 961-5945 (variant 2) | M1239 (variant 3) | ||
| 03S-0355b | 1 | 100.0 | 73.1 | 55.1 |
| 03S-0408 | 1 | 96.4 | 73.5 | 55.1 |
| 03S-0444 | 1 | 93.1 | 74.2 | 54.4 |
| 03S-0501 | 1 | 93.5 | 74.2 | 54.8 |
| 04S-0013 | 1 | 97.8 | 73.8 | 55.8 |
| 04S-0017 | 1 | 93.1 | 73.5 | 54.4 |
| 04S-0058b | 1 | 100.0 | 73.1 | 55.1 |
| 03S-0150 | 2 | 72.4 | 98.5 | 77.0 |
| 03S-0321 | 2 | 72.7 | 100.0 | 78.4 |
| 03S-0658 | 2 | 70.5 | 94.5 | 80.5 |
| 03S-0673 | 2 | 70.5 | 94.5 | 80.5 |
| 03S-0691 | 2 | 72.7 | 100.0 | 78.4 |
| 04S-0062 | 2 | 69.8 | 95.6 | 80.5 |
| 03S-0451 | 3 | 54.8 | 78.9 | 91.5 |
| 03S-0669 | 3 | 55.5 | 79.4 | 95.7 |
a
FHBP DNA sequencing was performed on all of the California isolates grouped as variant 2 or 3 by QPCR and on 7 of the 40 isolates identified as variant 1. The closest match to one of the three FHBP prototype sequences is shown in boldface.
b
Positive for reactivity with the MAb JAR-1 (23), which was raised against the FHBP from strain MC58.