TABLE 2.
Inhibition of cysteine uptake by cystinea
Concn (μM) | [35S]cysteine uptake (%)b | |
---|---|---|
Cystine | Cysteine | |
0 | 10 | 100 |
1 | 10 | 60 |
10 | 10 | 21 |
50 | 10 | 16 |
100 | 10 | 14 |
Inhibition studies were performed with the CYS-1 mutant of L. pneumophila as detailed in the text. Radiolabel and l-cysteine were held constant, and the concentration of cystine was varied.
The percentages represent the means for three replicates.