Lung leukocytes from week 2 infected untreated (Ctrl) or anti-CD4 Ab-treated mice were cultured for 24 h in the presence of heat-killed C. neoformans as a source of exogenous stimulation. Cytokines (A) IL-4, (B) IL-5, (C) IL-13, (D) IL-10, (E) IFN-γ, and (F) TNF-α were measured in the supernatants by ELISA. The results are the mean of two independent experiments (n ≥ 7 mice/group). *, P < 0.05; **, P < 0.005.