FIG. 5.

(A) Serum was obtained from untreated (Ctrl) and anti-CD4 Ab-treated mice infected for 2 or 3 weeks, and total serum IgE levels were determined by ELISA. IgE levels in anti-CD4 Ab-treated animals remained undetected at both time points. n ≥ 3 mice/group/time point. (B) Lungs were harvested at weeks 2 and 3 postinfection from untreated and anti-CD4 Ab-treated C. neoformans-infected mice, and CFU were determined. Data are representative of two independent experiments. n ≥ 6 mice/group/time point. There was no difference in lung CFU levels between the two groups.