FIG. 1.

Internalization of protein-coated microparticles into HeLa cells. HeLa cells were incubated with microparticles at a ratio of 100 microparticles/cell for 1 h at 37°C. Internalization was visualized by immunofluorescence staining. The cytoskeleton was stained with phalloidin (red). Extracellularly localized microparticles are green (arrowheads); intracellularly localized microparticles are blue (arrows). The results are representative of two independent experiments.