TABLE 1.
Subtracted sequence
|
Homology with H. pylori plasmids
|
H. pylori strains
|
|||||
---|---|---|---|---|---|---|---|
No. (%)
|
Pc | ||||||
Clonea | Length (bp) | GenBank accession no. | ORF, plasmid | Gene product and/or functionb | Ulcers (n = 15) | Gastritis (n = 30) | |
5p | 438 | DQ364775 | ORF4O, pHel4 | Putative | 5 (33.3) | 9 (30.0) | 0.909 |
12p | 727 | DQ364770 | ORF4C, pHel4 | MobA-like protein | 5 (33.3) | 9 (30.0) | 0.909 |
13p* | 491 | DQ364771 | ORF4M, pHel4 | Putative | 6 (40.0) | 16 (53.3) | 0.598 |
ORF4N, pHel4 | Putative | 6 (40.0) | 14 (46.7) | 0.916 | |||
24p | 353 | DQ364772 | ORF4N, pHel4 | Putative | 6 (40.0) | 14 (46.7) | 0.916 |
25p | 367 | DQ364779 | ORF4C, pHel4 | MobA-like protein | 5 (33.3) | 9 (30.0) | 0.909 |
62p | 677 | DQ364780 | repA, pHel5 | H. pylori replication protein A | 8 (53.3) | 17 (56.6) | 0.916 |
99p | 349 | DQ364781 | ORF4A, pHel4 | MccC-like protein | 4 (26.7) | 7 (23.3) | 0.902 |
B1-F1p* | 969 | DQ364776 | ORF4C, pHel4 | MobA-like protein | 5 (33.3) | 9 (30.0) | 0.909 |
ORF4F, pHel4 | MobC-like protein | 7 (46.6) | 9 (30.0) | 0.441 | |||
B1-F16p* | 935 | DQ364778 | ORF4A, pHel4 | MccC-like protein | 4 (26.7) | 7 (23.3) | 0.902 |
ORF4B, pHel4 | MccB-like protein | 4 (26.7) | 7 (23.3) | 0.902 |
*, Tested separately by dot blotting.
Gene product or function is according to Hofreuter and Haas (30).
The P value was determined by using the Fisher exact test.