TABLE 1.
Clinical descriptions of CDC Lyme disease patient seraa
| Pool | Patient identification | ELISA | Symptomology |
|---|---|---|---|
| Early localized | CDC 91-1222 | IgM+/IgG− | Single ECM, culture positive, 1-mo history |
| CDC 91-1347 | IgM+/IgG− | Single ECM, culture positive, 1-mo history | |
| CDC 91-1349 | IgM+/IgG− | Single ECM, culture positive, 1-mo history | |
| CDC 91-1350 | IgM+/IgG− | Single ECM, culture positive, 1-mo history | |
| CDC 91-1351 | IgM+/IgG− | Single ECM, culture positive, 1-mo history | |
| Early disseminated | CDC 90-2631 | IgM+/IgG+ | Single ECM, systemic illness, culture positive, 3-mo history |
| CDC 90-2668 | IgM+/IgG+ | Bell's palsy, systemic illness, Ab+, 2-mo history | |
| CDC 91-0865 | IgM+/IgG+ | Bell's palsy, ECM, Ab+, 6-wk history | |
| CDC 91-1104 | IgM+/IgG− | Multiple ECM, Ab+, 2-mo history | |
| CDC 91-1348 | IgM+/IgG+ | Single ECM, culture +, 3-mo history | |
| Late disseminated | CDC 91-0521 | IgM−/IgG+ | ECM, arthritis, Ab+, 5-mo history |
| CDC 91-0532 | IgM−/IgG+ | ECM, arthritis, CNS symptoms, Ab+, 13-yr history | |
| CDC 91-0533 | IgM+/IgG+ | Bell's palsy, arthritis, Ab+, 5-yr history | |
| CDC 91-0544 | IgM+/IgG+ | Arthritis, CNS symptoms, Ab+, 3 yr history | |
| CDC 92-0057 | IgM+/IgG+ | Severe CNS disease, culture positive, 4-yr history |
a
ELISA, enzyme-linked immunosorbent assay; ECM, erythema chronicum migrans; Ab+, B. burgdorferi Western blot positive; CNS, central nervous system.