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. 2006 Jul;50(7):2516–2521. doi: 10.1128/AAC.01226-05

TABLE 2.

Second-order rate constants of MFO, Toho-1, and TEM-1 against various antibiotics

Antibiotic kcat/Km (mM−1 s−1)
MFO Toho-1 TEM-1
Benzylpenicillin 1,000a 3,000c 84,000d
Nitrocefin 4,200a 2,700c 17,000d
Cephaloridine 660a 700c 2,200d
Cephalothin 1,900a 12,000c 650d
Cefotaxime 40b 2,100c 1.5d
Ceftazidime NDb 1.3c 0.07d
Cefoxitin 0.016b 0.00076c 0.006e
Imipenem 0.3b 2.25c 2.0e
a

Reference 1.

b

Reference 35; ND, not detectable.

c

Reference 18.

d

Reference 36.

e

Reference 14.