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PK parameters of unbound linezolid estimated by the integrated model after single and multiple linezolid dosinga
| i.v. dosing type | Vss (liter) | CLtot (liter/h) |
|---|---|---|
| Single (n = 12) | 61.4 (29.0) | 9.91 (45.0) |
| Multiple (n = 9) | 79.8 (23.6) | 8.44 (60.1) |
For Vss and CLtot, values in parentheses are cv (%) geometric means.
