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fAUC/MIC and fT>MIC values for linezolid in ultrafiltrated plasma and s.c. and i.m. ISF of critically ill patients after multiple dosinga
| Parameter |
fAUC/MIC in:
|
fT>MIC (%) in:
|
||||
|---|---|---|---|---|---|---|
| UF | ISF
|
UF | ISF
|
|||
| s.c. | i.m. | s.c. | i.m. | |||
 |
29.9 | 29.1 | 33.0 | 59 | 54 | 90 |
| Minimum | 12.0 | 10.1 | 14.1 | 16 | 0 | 24 |
| Maximum | 88.2 | 48.7 | 53.0 | 100 | 100 | 100 |
MIC = 4 mg/liter. For s.c. and i.m. ISF, n = 9. For ultrafiltrated plasma (UF), n = 10.
