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Survival of mice challenged with CpG ODN. Mice were randomly divided into five groups (n = 10 animals per group) and preinoculated with d-GalN (i.p., 600 mg/kg [weight]) 1 h before the experiment. Treatment groups are indicated by symbols as follows: □, saline alone; ▪, CpG ODN (10 mg/kg); +, CpG ODN and ART (50 mg/kg); ×, CpG ODN and ART (100 mg/kg); and ▵, CpG ODN and ART (200 mg/kg). *, P < 0.01; **, P < 0.05 versus the CpG ODN group.
